XMNI GG-POLYMORPHISM IN SIX UNRELATED PAKISTANI FAMILIES WITH INV/DEL GG(AGDB) DB-THALASSEMIA
Authors: Suhaib Ahmed1* and Masood Anwar2
1 Department of Pathology, PNS Shifa, Karachi, Pakistan
2 Department of Haematology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan
The XmnI Gg-polymorphism (C–T polymorphism at position -158 to the Gg-globin gene)
was studied in 13 individuals from six […]
SPECTRUM OF BETA-THALASSEMIA MUTATIONS IN VARIOUS REGIONS OF PUNJAB AND ISLAMABAD, PAKISTAN: ESTABLISHMENT OF PRENATAL DIAGNOSIS
Authors: Shahid Mahmood Baig,* Ayesha Azhar,* Hammad Hassan
Abstract:
We present here an analysis of 888 unrelated beta-thal chromosomes consisting of 444 transfusion dependent children from various regions of Punjab and Islamabad Pakistan. By using Multiplex ARMS- PCR, restriction endonuclease analysis, allele specific oligonucleotide (ASO) hybridization and sequencing, 17 […]
IRANIAN NATIONAL THALASSAEMIA SCREENING PROGRAMME
PREMARITAL SCREENING FOR B-THALASSAEMIA IN SOUTHERN IRAN: OPTIONS FOR IMPROVING THE PROGRAMME
Authors: Mehran Karimi, Nima Jamalian, HoomanYarmohammadi, Abdolrasoul Askarnejad, Abdolreza Afrasiabi and Alireza Hashemi
Background b-thalassaemia is a preventable disease. Iran has about 20,000 homozygote
b-thalassaemia patients and 3,750,000 carriers.
Objective To assess the 10-year results of the screening programme, which has been operating in
Southern Iran […]
THE EFFECT OF CHORIONIC VILLUS SAMPLING ON FETAL HEART RATE
Author: Shahram Akhlaghpoor Taraneh Hosseinipoor
Novin Medical Radiation Institute, Tehran, Iran
Abstract
Objective: Fetal heart rate (FHR) variation during chorionic villus sampling (CVS) is a controversial topic. Limited
studies have been published on this subject. Our study intended to evaluate the effects of CVS on the […]
