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The Effect of Chorionic Villus Sampling on Fetal Heart Rate

Author: Shahram Akhlaghpoor Taraneh Hosseinipoor

Novin Medical Radiation Institute, Tehran, Iran

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Objective: Fetal heart rate (FHR) variation during chorionic
villus sampling (CVS) is a controversial topic. Limited
studies have been published on this subject. Our
study intended to evaluate the effects of CVS on the FHR.
Method: One hundred and sixty-five patients undergoing
first-trimester elective CVS for prenatal diagnosis of
ß-thalassemia were entered into a prospective study. Mmode
FHR was obtained before and immediately after
CVS in the patients. Potentially confounding variables
also recorded included: gestational age, number of needle
passes and placental location. Results: FHR values
before and after CVS were compared using the paired t
test and showed no statistically significant differences by
95% confidence. No differences were found in data analyzing
gestational age, number of needle passes or placental
location. Conclusion: We were unable to detect
any significant change in FHR after performing CVS. It
seems that FHR is generally not altered by CVS.